Human CLDN2 Protein; hFc Tag

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£219.00

SKU:: PME100782
Additional Names:: Claudin-2;SP82
Molecular Weight:: The protein has a predicted molecular mass of 31.4 kDa after removal of the signal peptide. The apparent molecular mass of CLDN2-hFc is approximately 25-35 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CLDN2
CLDN2(Ser29-Gln78) hFc(Glu99-Ala330):: CLDN2(Ser29-Gln78) hFc(Glu99-Ala330)
Extra Details:: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq; Jan 2010]