PME100714
Human HSD17B10 Protein; S Tag
Size
£181.00
- SKU:
- PME100714
- Additional Names:
- MHBD;Type II HADH;ERAB;HADH2;MRPP2;SCHAD;SDR5C1;XH98G2
- Molecular Weight:
- The protein has a predicted molecular mass of 28.5 kDa after removal of the signal peptide. The apparent molecular mass of S-HSD17B10 is approximately 35-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- HSD17B10
- S tag HSD17B10(Ala2-Pro261):
- S tag HSD17B10(Ala2-Pro261)
- Extra Details:
- This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II; a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids; and is a subunit of mitochondrial ribonuclease P; which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease; and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified; but the full-length nature of only two transcript variants has been determined. [provided by RefSeq; Aug 2014]
- Shipping Conditions:
- Ambient