PME100710
Human DAP10 Protein; hFc Tag
Size
£171.00
- SKU:
- PME100710
- Additional Names:
- HCST;KAP10;PIK3AP
- Molecular Weight:
- The protein has a predicted molecular mass of 29.1 kDa after removal of the signal peptide. The apparent molecular mass of DAP10-hFc is approximately 25-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- DAP10
- DAP10(Gln19-Pro48) hFc(Glu99-Ala330):
- DAP10(Gln19-Pro48) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. The encoded protein may form part of the immune recognition receptor complex with the C-type lectin-like receptor NKG2D. As part of this receptor complex; this protein may activate phosphatidylinositol 3-kinase dependent signaling pathways through its intracytoplasmic YxxM motif. This receptor complex may have a role in cell survival and proliferation by activation of NK and T cell responses. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq; Jul 2008]
- Shipping Conditions:
- Ambient