PME100696
Human IGFBP7 Protein; hFc Tag
Size
£171.00
- SKU:
- PME100696
- Additional Names:
- IBP-7;TAF;IGFBP-rP1;MAC25 protein
- Molecular Weight:
- The protein has a predicted molecular mass of 52.3 kDa after removal of the signal peptide. The apparent molecular mass of hFc-IGFBP7 is approximately 55-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- IGFBP7
- hFc(Glu99-Ala330) IGFBP7(Asp30-Leu282):
- hFc(Glu99-Ala330) IGFBP7(Asp30-Leu282)
- Extra Details:
- This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq; Dec 2011]
- Shipping Conditions:
- Ambient