PME100682
Human IFNB1 Protein; hFc Tag
Size
£177.00
- SKU:
- PME100682
- Additional Names:
- IFB;IFF;IFN-beta;IFNB
- Molecular Weight:
- The protein has a predicted molecular mass of 46.2 kDa after removal of the signal peptide. The apparent molecular mass of IFNB1-hFc is approximately 40-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- IFNB1
- IFNB1(Met22-Asn187) hFc(Glu99-Ala330):
- IFNB1(Met22-Asn187) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes a cytokine that belongs to the interferon family of signaling proteins; which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons; which are important for defense against viral infections. In addition; type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen; type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq; Sep 2015]
- Shipping Conditions:
- Ambient