PME100675
Human MMP14 Protein; hFc Tag
Size
£219.00
- SKU:
- PME100675
- Additional Names:
- MMP-14;MMP-X1;MT-MMP;MT-MMP 1;MT1-MMP;MT1MMP;MTMMP1;WNCHRS
- Molecular Weight:
- The protein has a predicted molecular mass of 75.3 kDa after removal of the signal peptide. The apparent molecular mass of MMP14-hFc is approximately 55-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- MMP14
- MMP14(Tyr112-Ala541) hFc(Glu99-Ala330):
- MMP14(Tyr112-Ala541) hFc(Glu99-Ala330)
- Extra Details:
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; and tissue remodeling; as well as in disease processes; such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However; the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein; and this activity may be involved in tumor invasion. [provided by RefSeq; Jul 2008]
- Shipping Conditions:
- Ambient