PME100572
Human SLC7A11 Protein; hFc Tag
Size
£171.00
- SKU:
- PME100572
- Additional Names:
- CCBR1;xCT
- Molecular Weight:
- The protein has a predicted molecular mass of 33.4 kDa after removal of the signal peptide.The apparent molecular mass of SLC7A11-hFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- SLC7A11
- SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) (Thr219-Leu317) (Asp386-Ser387) (Ser445-Pro447) hFc(Glu99-Ala330):
- SLC7A11(Lys67-Gly74) (Leu151-Cys158) (Lys215-Thr233) (Thr219-Leu317) (Asp386-Ser387) (Ser445-Pro447) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes a member of a heteromeric; sodium-independent; anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system; designated Xc(-); the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also; increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels; resulting in neuronal cell death. [provided by RefSeq; Sep 2011]
- Shipping Conditions:
- Ambient