PME100566
Human NTRK3 Protein; hFc Tag
Size
£171.00
- SKU:
- PME100566
- Additional Names:
- gp145(trkC);GP145-TrkC;TRKC
- Molecular Weight:
- The protein has a predicted molecular mass of 70.9 kDa after removal of the signal peptide.The apparent molecular mass of NTRK3-hFc is approximately 100-130 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- NTRK3
- NTRK3(Cys32-Thr429) hFc(Glu99-Ala330):
- NTRK3(Cys32-Thr429) hFc(Glu99-Ala330)
- Extra Details:
- This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that; upon neurotrophin binding; phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas; secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq; Jul 2011]
- Shipping Conditions:
- Ambient