PME100564
Human GM-CSF Protein; hFc Tag
Size
£219.00
- SKU:
- PME100564
- Additional Names:
- CSF;GMCSF
- Molecular Weight:
- The protein has a predicted molecular mass of 40.6 kDa after removal of the signal peptide.The apparent molecular mass of GM-CSF-hFc is approximately 35-70 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- GM-CSF
- GM-CSF(Ala18-Glu144) hFc(Glu99-Ala330):
- GM-CSF(Ala18-Glu144) hFc(Glu99-Ala330)
- Extra Details:
- The protein encoded by this gene is a cytokine that controls the production; differentiation; and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31; which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4; 5; and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines; including the one produced by this gene; have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis. [provided by RefSeq; Aug 2020]
- Shipping Conditions:
- Ambient