PME100558
Human IL18 Protein; mFc Tag
Size
£219.00
- SKU:
- PME100558
- Additional Names:
- IGIF;IL-1g;IL-18;IL1F4
- Molecular Weight:
- The protein has a predicted molecular mass of 44.3 kDa after removal of the signal peptide.The apparent molecular mass of IL18-mFc is approximately 35-55 kDa due to glycosylation.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- IL18
- IL18(Tyr37-Asp193) mFc(Pro99-Lys330):
- IL18(Tyr37-Asp193) mFc(Pro99-Lys330)
- Extra Details:
- The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1; and is capable of stimulating interferon gamma production; and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs; and in potentially fatal conditions characterized by a cytokine storm. In humans; IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq; Aug 2020]
- Shipping Conditions:
- Ambient