Human GUCY2C Protein; His Tag

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£181.00

SKU:: PME100262
Additional Names:: DIAR6;GC-C;GUC2C;MECIL;MUCIL;STAR
Molecular Weight:: The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of GUCY2C-His is approximately 55-130 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: GUCY2C
GUCY2C(Ser24-Gln430) 6×His tag:: GUCY2C(Ser24-Gln430) 6×His tag
Extra Details:: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin; and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq; Nov 2016]