Human 5T4 Protein; His Tag

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£171.00

SKU:: PME100123
Additional Names:: 5T4;5T4AG;M6P1;WAIF1
Molecular Weight:: The protein has a predicted molecular mass of 36.1 kDa after removal of the signal peptide.The apparent molecular mass of 5T4-His is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: 5T4
5T4(Ser32-Ser355) 6×His tag:: 5T4(Ser32-Ser355) 6×His tag
Extra Details:: This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.