Human CD44 Protein; His Tag

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£171.00

SKU:: PME100108
Additional Names:: CD44;CDW44;CSPG8;ECMR-III;HCELL;HUTCH-I;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;Epican
Molecular Weight:: The protein has a predicted molecular mass of 22.9 kDa after removal of the signal peptide.The apparent molecular mass of CD44-His is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CD44
CD44(Gln21-Pro220) 6×His tag:: CD44(Gln21-Pro220) 6×His tag
Extra Details:: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions; cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands; such as osteopontin; collagens; and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation; recirculation and homing; hematopoiesis; and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however; the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein; and may be related to tumor metastasis.

Shipping Conditions:: Ambient