Human AFP Protein; hFc Tag

Size

£184.00

SKU:: PME100075
Additional Names:: AFPD;FETA;HPAFP
Molecular Weight:: The protein has a predicted molecular mass of 92.6 kDa after removal of the signal peptide.The apparent molecular mass of AFP-hFc is approximately 100-130 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: AFP
AFP(Arg19-Val609) hFc(Glu99-Ala330):: AFP(Arg19-Val609) hFc(Glu99-Ala330)
Extra Details:: This gene encodes alpha-fetoprotein; a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma; and has prognostic value for managing advanced gastric cancer. However; hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin; and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms; and binds copper; nickel; fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Shipping Conditions:: Ambient