PME100063
Human CLDN6 Protein; mFc Tag
Size
£171.00
- SKU:
- PME100063
- Additional Names:
- Claudin 6;Claudin-6;Skullin
- Molecular Weight:
- The protein has a predicted molecular mass of 31.6 kDa after removal of the signal peptide.
- Purity:
- The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CLDN6
- CLDN6(Met1-Ala4) (Gln57-Gln78) (Arg145-Arg158) mFc(Pro99-Lys330):
- CLDN6(Met1-Ala4) (Gln57-Gln78) (Arg145-Arg158) mFc(Pro99-Lys330)
- Extra Details:
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet; with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands; which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.[provided by RefSeq; Aug 2010]
- Shipping Conditions:
- Ambient