Human NTB-A Protein; mFc-His Tag

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£171.00

SKU:: PME100059
Additional Names:: NTB-A;SLAMF6;Ly108;NK-T-B-antigen;CD352;KALI
Molecular Weight:: The protein has a predicted molecular mass of 50.1 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: NTB-A
NTB-A(Gln22-Met226) mFc(Pro99-Lys330) 6×His tag:: NTB-A(Gln22-Met226) mFc(Pro99-Lys330) 6×His tag
Extra Details:: The protein encoded by this gene is a type I transmembrane protein; belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK); T; and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Shipping Conditions:: Ambient