Human CD70 Protein; mFc-His Tag

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£195.00

SKU:: PME100042
Additional Names:: CD70;CD27LG;TNFSF7;TNFSF7G;CD27L
Molecular Weight:: The protein has a predicted molecular mass of 45.6 kDa after removal of the signal peptide.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CD70
mFc(Pro99-Lys330) CD70(Gln39-Pro193) 6×His:: mFc(Pro99-Lys330) CD70(Gln39-Pro193) 6×His
Extra Details:: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated; but not on resting; T and B lymphocytes. It induces proliferation of costimulated T cells; enhances the generation of cytolytic T cells; and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation; cytotoxic function of natural killer cells; and immunoglobulin sythesis.