Mouse ACVR2A Protein; hFc Tag

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£189.00

SKU:: PME-M100115
Additional Names:: Acvr2; ActrIIa; TactrII
Molecular Weight:: The protein has a predicted molecular mass of 39.6 kDa after removal of the signal peptide. The apparent molecular mass of mACVR2A-hFc is approximately 35-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ACVR2A
Mouse ACVR2A(Ala20-Pro135) hFc(Glu99-Ala330):: Mouse ACVR2A(Ala20-Pro135) hFc(Glu99-Ala330)
Extra Details:: Enables several functions; including BMP receptor activity; PDZ domain binding activity; and activin binding activity. Acts upstream of or within several processes; including Sertoli cell proliferation; copulation; and embryonic skeletal system development. Located in cell surface. Is expressed in several structures; including central nervous system; early conceptus; gonad; gut; and sensory organ. Used to study Weissenbacher-Zweymuller syndrome. Human ortholog(s) of this gene implicated in colon cancer. Orthologous to human ACVR2A (activin A receptor type 2A). [provided by Alliance of Genome Resources; Apr 2022]

Shipping Conditions:: Ambient