Mouse CCR2 Protein; hFc Tag

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£169.00

SKU:: PME-M100107
Additional Names:: Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2
Molecular Weight:: The protein has a predicted molecular mass of 32.3 kDa after removal of the signal peptide. The apparent molecular mass of mCCR2-hFc is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target:: CCR2
Mouse CCR2(Met1-Ala55) hFc(Glu99-Ala330):: Mouse CCR2(Met1-Ala55) hFc(Glu99-Ala330)
Extra Details:: Enables C-C chemokine binding activity and C-C chemokine receptor activity. Involved in several processes; including leukocyte migration; positive regulation of cell migration; and regulation of cytokine production. Acts upstream of or within several processes; including cellular defense response; monocyte chemotaxis; and neutrophil clearance. Located in external side of plasma membrane. Is expressed in several structures; including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Used to study Coronavirus infectious disease and age related macular degeneration. Human ortholog(s) of this gene implicated in several diseases; including Kawasaki disease; aggressive periodontitis; coronary artery disease (multiple); glucose metabolism disease (multiple); and uveitis (multiple). Orthologous to human CCR2 (C-C motif chemokine receptor 2). [provided by Alliance of Genome Resources; Apr 2022]

Shipping Conditions:: Ambient