Mouse BMP6 Protein; His Tag

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£224.00

SKU:: PME-M100075
Additional Names:: BMP-6;VGR-1
Molecular Weight:: The protein has a predicted molecular mass of 54.9 kDa after removal of the signal peptide. The apparent molecular mass of mBMP6-His is approximately 35-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: BMP6
Mouse BMP6(Cys21-His510) 6×His tag:: Mouse BMP6(Cys21-His510) 6×His tag
Extra Details:: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis; fat and bone development; and ovulation. Mice lacking this gene exhibit delayed ossification of the sternum; iron overload; and reduced fertility in females. [provided by RefSeq; Jul 2016]

Shipping Conditions:: Ambient