Mouse TIGIT Protein; hFc Tag

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£202.00

SKU:: PME-M100053
Additional Names:: T-cell immunoreceptor with Ig and ITIM domains;V-set and transmembrane domain-containing protein 3;Vstm3
Molecular Weight:: The protein has a predicted molecular mass of 38.6 kDa after removal of the signal peptide. The apparent molecular mass of mTIGIT-hFc is approximately 40-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: TIGIT
Mouse TIGIT(Ile28-Pro139) hFc(Glu99-Ala330):: Mouse TIGIT(Ile28-Pro139) hFc(Glu99-Ala330)
Extra Details:: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq; Sep 2009]

Shipping Conditions:: Ambient