Mouse B7-H2 Protein; hFc Tag

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£202.00

SKU:: PME-M100047
Additional Names:: ICOSLG;B7H2;B7RP-1;B7RP1;CD275;GL50;ICOS-L;ICOSL;LICOS;ICOS ligand
Molecular Weight:: The protein has a predicted molecular mass of 52.4 kDa after removal of the signal peptide. The apparent molecular mass of mB7-H2-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: B7-H2
Mouse B7-H2(Glu47-Lys279) hFc(Glu99-Ala330):: Mouse B7-H2(Glu47-Lys279) hFc(Glu99-Ala330)
Extra Details:: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions; as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).[UniProtKB/Swiss-Prot Function]

Shipping Conditions:: Ambient