Mouse Mesothelin Protein; His Tag

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£202.00

SKU:: PME-M100040
Additional Names:: Mesothelin;Pre-pro-megakaryocyte-potentiating factor
Molecular Weight:: The protein has a predicted molecular mass of 35.0 kDa after removal of the signal peptide. The apparent molecular mass of mMesothelin-His is approximately 35-40 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: Mesothelin
Mouse Mesothelin(Asp298-Ser600) 6×His tag:: Mouse Mesothelin(Asp298-Ser600) 6×His tag
Extra Details:: This gene encodes a preproprotein that is proteolytically processed to generate two protein products; megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas; ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq; Feb 2016]

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