Mouse CD47 Protein; hFc Tag

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£171.00

SKU:: PME-M100012
Additional Names:: 9130415E20Rik;AA407862;AI848868;AW108519;B430305P08Rik;IAP;Itgp
Molecular Weight:: The protein has a predicted molecular mass of 40.0 kDa after removal of the signal peptide.The apparent molecular mass of mCD47-hFc is approximately 55-70 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CD47
Mouse CD47(Gln19-Lys140) hFc(Glu99-Ala330):: Mouse CD47(Gln19-Lys140) hFc(Glu99-Ala330)
Extra Details:: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets; and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus. Receptor for SIRPA; binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion; enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection (By similarity).[UniProtKB/Swiss-Prot Function]

Shipping Conditions:: Ambient