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PME-C100053

Cynomolgus CD3D Protein; His Tag

Size

£199.00

SKU:
PME-C100053
Additional Names:
CD3-DELTA; IMD19; T3D
Molecular Weight:
The protein has a predicted molecular mass of 10.9 kDa after removal of the signal peptide.
Purity:
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CD3D
CD3D(Phe22-Ala105) 10×His tag:
CD3D(Phe22-Ala105) 10×His tag
Extra Details:
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex; and along with four other CD3 subunits; binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist; but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq; Feb 2009]
Shipping Conditions:
Ambient