Cynomolgus CD3E Protein; hFc Tag

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£219.00

SKU:: PME-C100037
Additional Names:: T3E; TCRE; IMD18; CD3epsilon
Molecular Weight:: The protein has a predicted molecular mass of 37.0 kDa after removal of the signal peptide. The apparent molecular mass of cCD3E-hFc is approximately 35-55 kDa due to glycosylation.
Purity:: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target:: CD3E
CD3E(Gln22-Asp117) hFc(Glu99-Ala330):: CD3E(Gln22-Asp117) hFc(Glu99-Ala330)
Extra Details:: The protein encoded by this gene is the CD3-epsilon polypeptide; which together with CD3-gamma; -delta and -zeta; and the T-cell receptor alpha/beta and gamma/delta heterodimers; forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon; gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq; Jul 2008]

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