Human CCR7 full length protein-MNP

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£1,290.00

SKU:: FLP200060
Additional Names:: BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1
Molecular Weight:: The human full length CCR7 protein has a MW of 42.9 kDa
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from PBS. Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Target:: CCR7
Chemokine signaling pathway; Cytokine-cytokine receptor interaction:: Chemokine signaling pathway; Cytokine-cytokine receptor interaction
Extra Details:: The protein is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV); and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues; as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes; and may also function in the activation and polarization of T cells; and in chronic inflammation pathogenesis.

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