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FLP120621

Human CLCN4-Strep full length protein-synthetic nanodisc

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£903.00

SKU:
FLP120621
Additional Names:
CLC4; ClC-4; ClC-4A; MRX15; MRX49; MRXSRC
Molecular Weight:
The human full length CLCN4-Strep protein has a MW of 84.9 kDa
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Formulation:
Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl; 150 mM NaCl; pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:
CLCN4
Extra Details:
The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7; Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I); which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq; Mar 2012]
Shipping Conditions:
Ambient