Human ASIC2-Strep full length protein-synthetic nanodisc

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£903.00

SKU:: FLP120607
Additional Names:: ACCN; ACCN1; ASIC2a; BNC1; BNaC1; MDEG; hBNaC1
Molecular Weight:: The human full length ASIC2-Strep protein has a MW of 57.7 kDa
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl; 150 mM NaCl; pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: ASIC2
Extra Details:: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini; 2 hydrophobic transmembrane regions; and a large extracellular loop; which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition; a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants; encoding distinct isoforms; have been identified. [provided by RefSeq; Feb 2012]

Shipping Conditions:: Ambient