Human DRD2 full length protein-synthetic nanodisc

Size

£992.00

SKU:: FLP100230
Additional Names:: D2DR; D2R
Molecular Weight:: The human full length DRD2 protein has a MW of 50.6 kDa
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl; 150 mM NaCl; pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: DRD2
Gap junction; Neuroactive ligand-receptor interaction:: Gap junction; Neuroactive ligand-receptor interaction
Extra Details:: This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described; but it has not been determined whether this form is normal or due to aberrant splicing.