FLP100006
Human CLDN18.2 full length protein-VLP
Size
£1,290.00
- SKU:
- FLP100006
- Additional Names:
- Claudin 18.2
- Molecular Weight:
- The Human CLDN18.2 Protein has a predicted MW of 29 kDa.Due to PTM; the actual MW on SDS-PAGE gel is around 50kDa.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Target:
- CLDN18.2
- Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Tight junction:
- Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Tight junction
- Extra Details:
- The protein encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets; and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq; Jun 2010]
- Shipping Conditions:
- Ambient