Human CLDN6 full length protein -MNP

Size

£1,290.00

SKU:: FLP100004
Additional Names:: Claudin 6; Claudin-6; Skullin;Claudin6
Molecular Weight:: The human full length CLDN6 Protein has a MW of 23 kDa
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Target:: CLDN6
Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Tight junction:: Cell adhesion molecules (CAMs); Leukocyte transendothelial migration; Tight junction
Extra Details:: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets; forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet; with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands; which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

Shipping Conditions:: Ambient