DME101288
Anti-APLP2 antibody(1F12); Rabbit mAb
Size
£198.00
- SKU:
- DME101288
- Additional Names:
- APLP-2;APPH;APPL2;CDEBP
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing).
- Supplier:
- DIMA Biotechnology Ltd
- Host:
- Rabbit
- Reactivities:
- Human
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Clone:
- 1F12
- Target:
- APLP2
- Extra Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2); which is a member of the APP (amyloid precursor protein) family including APP; APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-; copper- and zinc- binding domains at the N-terminus; BPTI/Kunitz inhibitor and E2 domains in the middle region; and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission; spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq; Aug 2011]
- Shipping Conditions:
- Blue Ice