DME101025
Anti-Dxd antibody(1A5); Rabbit mAb
Size
£198.00
- SKU:
- DME101025
- Additional Names:
- N.A.
- Application:
- ELISA
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Host:
- Rabbit
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Clone:
- 1A5
- Target:
- Dxd
- Extra Details:
- Dxd is a potent anti-cancer drug; acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA; impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs); with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.
- Shipping Conditions:
- Ambient