Anti-CD3E antibody(1G2); IgG1 Chimeric mAb

Size

£198.00

SKU:: DMC101085
Additional Names:: CD3e;T3E
Application:: Flow Cytometry
Purification:: Purified from cell culture supernatant by affinity chromatography
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Host:: Rabbit
Reactivities:: Human
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Clone:: 1G2
Target:: CD3E
Extra Details:: The protein encoded by this gene is the CD3-epsilon polypeptide; which together with CD3-gamma; -delta and -zeta; and the T-cell receptor alpha/beta and gamma/delta heterodimers; forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon; gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq; Jul 2008]