Anti-YAP1 antibody(DMC495); IgG1 Chimeric mAb

Size

£198.00

SKU:: DMC100495
Additional Names:: COB1; YAP; YAP2; YAP65; YKI
Application:: Flow Cytometry
Purification:: Purified from cell culture supernatant by affinity chromatography
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Host:: Rabbit
Reactivities:: Human
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Clone:: DMC495
Target:: YAP1
Extra Details:: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development; growth; repair; and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.