DMC100440
Anti-UPA antibody(DMC440); IgG1 Chimeric mAb
Size
£198.00
- SKU:
- DMC100440
- Additional Names:
- ATF; BDPLT5; QPD; u-PA; UPA; URK
- Application:
- Flow Cytometry
- Purification:
- Purified from cell culture supernatant by affinity chromatography
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Host:
- Rabbit
- Reactivities:
- Human
- Formulation:
- Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
- Clone:
- DMC440
- Target:
- UPA
- Extra Details:
- This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants; at least one of which encodes an isoform that is proteolytically processed.
- Shipping Conditions:
- Ambient