Anti-EDA antibody(DMC388); IgG1 Chimeric mAb

Size

£198.00

SKU:: DMC100388
Additional Names:: ED1; EDA2
Application:: Flow Cytometry
Purification:: Purified from cell culture supernatant by affinity chromatography
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Host:: Rabbit
Reactivities:: Human
Formulation:: Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Clone:: DMC388
Target:: EDA
Extra Details:: The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein; which belongs to the tumor necrosis factor family; acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia; anhidrotic; which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.