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DMC100222

Anti-PCSK9 antibody(DMC222); IgG1 Chimeric mAb

Size

£198.00

SKU:
DMC100222
Additional Names:
FH3; FHCL3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9
Application:
ELISA, Flow Cytometry
Purification:
Purified from cell culture supernatant by affinity chromatography
Storage Conditions:
Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:
DIMA Biotechnology Ltd
Host:
Rabbit
Reactivities:
Human
Formulation:
Lyophilized from sterile PBS; pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Clone:
DMC222
Target:
PCSK9
Extra Details:
This gene encodes a member of the subtilisin-like proprotein convertase family; which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver; intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Ambient