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Back to blog Accelerating Immune Cell Growth In Vitro

Accelerating Immune Cell Growth In Vitro

A Breakthrough in human immune cell expansion with IQ Biosciences cell solutions and Fujifilm's Animal free Media to boost T and NK cell production from lab to pre-clinical research.

In the rapidly evolving field of immunotherapy, the importance of robust, high expansion of well characterised T and NK cells cannot be overstated.  

In vitro cultivation of immune cells is fraught with difficulties. These cells often have reduced viability after freezing and thawing, and they typically have short lifespans in ex-vivo culture. Additionally, immune cells need to be fully activated to maintain their functionality, which can be complex to achieve and sustain.

The combination of IQ Biosciences' high-quality immune cells from healthy donor PBMCs isolated to highly viable T cells and NK cells and Fujifilm's innovative optimised Animal Free cell culture media specialised for T-cells and NK cells, along with CT grade GMP cytokine growth factors represent a significant step forward in in vitro primary human immune cell research.

This synergistic approach will address the key challenges of T and NK cell growths, enabling researchers to conduct more effective and reliable end to end studies by transforming the approach from the lab to preclinical studies.

IQBioscience immune cell solutions have been used for development of assays and drug therapeutics and therefore as a trusted supplier offers highly viable and purified isolated T cells that can be Treg, isolated CD4+T cells or CD8+T cells, NK cells, isolated PBMC and many more.

Fujifilm offers Xeno Free Media for the expansion of different T-cells and NK-cells combined with their GMP CT grade cytokine growth factor that can enhance the culture process

PRIME-XV T Cell CDM: medium ensures consistent vigorous T cell growth, maintains T cell viability and expansion and offers efficient transduction of T cells without need for enhancers

  • Supports T cell expansion without addition of serum and is animal component free due to which they can exclude any genetic modification
  • Supports all ex vivo rapid T cell growth and viability like Th1, Th2, Th9, Th17, Tregs, Th22

PRIME-XV T Cell Expansion XSFM: reduces the risk of contamination and lot-to-lot variability, optimises T cell expansion of CD4+ and CD8+ that are critical for CAR-T therapy and maintain T-cell potency, functionality and growth in the engineered CAR-T cells

Note: The media requires cytokine growth factors based on end user application. Fujifilms offers more than 300 Recombinant growth factors that can be used for various T-Cell, MSCs, HSCs, CAR-T, CAR TCR, CAR-NK applications

PRIME-XV NK Cell CDM is the first commercial chemically defined, animal component-free medium for the ex vivo expansion of natural killer (NK) and NKT cells.

  • Supports robust cell expansion and viability of CD56+ cells in heterogeneous peripheral blood mononuclear cell (PBMC) culture
  • Supports expansion of NK cells when supplemented with Interleukin (IL)-2, IL-12, IL-18, and IL-21 from viable PBMCs
  • Supports NKT cell expansion when supplemented with IL-2 from viable PBMCs
  • Maintains high NK and NKT cytotoxic capability

Cell

Cytokines associated

Related Media

Th1- T helper type 1

IL-2; IL-10

T cell CDM-91154,
T cell XSFM-91141

Th2- T helper type 2

IL-2; IL-6; IL-21

T cell CDM-91154,
T cell XSFM-91141

Th9- T helper type 9

IL-10

T cell CDM-91154,
T cell XSFM-91141

Th17- T helper type 17

IL-6; IL-21

T cell CDM-91154,
T cell XSFM-91141

Tfh- T Follicular helper

IL-2; IL-6; IL-10; IL-21

T cell CDM-91154,
T cell XSFM-91141

Treg-Regulatory T

IL-2; IL-10

T cell CDM-91154,
T cell XSFM-91141

Th22- T helper type 22

IL-6; IL-10; IL-21

T cell CDM-91154,
T cell XSFM-91141

NK-Natural Killer T

IL-10

T cell CDM-91154,
T cell XSFM-91141

NK-Natural Killer

IL-2; IL-7; IL-10; IL-15

NK CDM-91215