1457
Lymphoid enhancer-binding factor 1 Adenovirus (Ad-LEF1)
Size
£882.00
- SKU:
- 1457
- Additional Names:
- Ad-LEF1|Lymphoid enhancer-binding factor 1 Adenovirus
- Concentration:
- 1E10 PFU/ml
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Vector Biolabs
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Species:
- Virus
- Extra Details:
- T-cell factor (TCF-1) and lymphoid enhancer-binding factor (for LEF-1, also designated TCF-1(alpha)) compose a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription factors are activated by the Wnt-1 and Wingless pathways and are characterized by the presence of a conserved protein motif, the high mobility group (HMG) 1 box, which mediates DNA binding. LEF-1, TCF-1, and two other family members, TCF-3 and TCF-4, directly bind to cytosolic beta-catenin and facilitate its translocation to the nucleus, where these complexes induce expression of Wnt target genes., vectorbiolabs
- Shipping Conditions:
- Dry Ice