TCF4 (dn) Adenovirus (Ad-TCF4 (dn))

Size

£631.00

SKU:: 1281
Additional Names:: Ad-TCF4 (dn)|TCF4 (dn) Adenovirus
Concentration:: 1E10 PFU/ml
Storage Conditions:: -70[o]C Avoid freeze/thaw cycles.
Supplier:: Vector Biolabs
Buffer:: DMEM, 2% BSA, 2.5% Glycerol
Species:: Virus
Extra Details:: T cell factor-4 (Tcf-4) plays an important role in development and carcinogenesis. It directly binds to cytosolic B Beta-catenin and facilitate its translocation to the nucleus. In the nucleus, these complexes induce expression various target genes. The adenovirus expresses a dominant negative TCF4. Reference: He TC., et al., Science. 1998 Sep 4;281(5382):1509-12., vectorbiolabs