1180
NIK Adenovirus (Ad-CMV-NIK)
Size
£631.00
- SKU:
- 1180
- Additional Names:
- Ad-CMV-NIK|NIK Adenovirus
- Concentration:
- 1E10 PFU/ml
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Vector Biolabs
- Buffer:
- DMEM, 2% BSA, 2.5% Glycerol
- Species:
- Virus
- Extra Details:
- NFIB-Inducing Kinase (NIK) The NFIB transcription factor can be activated by several cytokines including TNF and IL-1. The TNF receptor activates NFIB through the Traf2 adapter protein , whereas the IL-1 receptor activates NFIB in a pathway involving Traf6 . Both Traf2 and Traf6 have been shown to interact with a serine/threonine kinase designated NFkB inducing kinase (NIK), which appears to participate in the NFIB signaling cascades triggered by both TNF and IL-1. NIK associates with, and is a costimulator for IkB kinase I+/- (IKKA Alpha). IKKA Alpha , in turn, phosphorylates IIB, resulting in I I B degradation and NF I B activation. NIK has sequence similarity to several kinases that participate in MAP kinase cascades., vectorbiolabs
- Shipping Conditions:
- Dry Ice