ZBTB7B, ID (Zinc Finger And BTB Domain-containing Protein 7B, Zinc Finger Protein 67 Homolog, Zfp-67, Zinc Finger And BTB Domain-containing Protein 15, Zinc Finger Protein Th-POK, T-helper-inducing POZ/Krueppel-like Factor, Krueppel-related Zinc Finger Protein cKrox, hcKrox, ZBTB15, ZFP67)

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£696.00

SKU:: Z0737-67A
Purity:: Purified by ammonium sulfate precipitation
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the center region of human ZBTB7B (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice