XRCC5 (X Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-strand-break Rejoining), X-ray Repair Cross-complementing Protein 5, 86kD Subunit of Ku Antigen, ATP Dependent DNA Helicase 2 Subunit 2, ATP-dependent DNA Helicase II, ATP-dependent DNA Helicase II 80kD Subunit, CTC Box Binding Factor 85kD, CTC85, CTCBF, DNA Repair Protein XRCC5, FLJ39089, G22P2, Ku 80, Ku80, Ku Autoantigen 80kD, Ku 86, Ku86, Ku86 Autoantigen-related Protein 1, KARP1, KARP-1, KUB2, Lupus Ku Autoantigen Protein p86, Nuclear Factor IV, NFIV, Thyroid Lupus Autoantigen, TLAA)

Size

£642.00

SKU:: X9505-02B
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-SLAKKDEKTDTLED, at the internal region of human XRCC5.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Telomere length maintenance, an activity essential for chromosome stability and genome integrity, is regulated by telomerase- and telomere-associated factors. The DNA repair protein Ku (a heterodimer of Ku70 and Ku80 subunits) associates with mammalian telomeres and contributes to telomere maintenance. The Ku heterodimer functions at two kinds of DNA ends: telomeres and double-strand breaks. The role that Ku plays at these two classes of termini must be distinct, because Ku is required for accurate and efficient joining of double-strand breaks while similar DNA repair events are normally prohibited at chromosome ends. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA: 1:16,000 Western Blot: 0.1-0.3ug/ml, observed in lysates of HeLa on ~80-85kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice