Urokinase Plasminogen Activator (uPA) (Not for Export EU)

Size

£429.00

SKU:: U1820-11C
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Purified human urokinase plasminogen activator [uPA]
Format:: Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute in ddH2O.
Extra Details:: Urokinase plasminogen activator (uPA) is a serine protease. It converts the abundant proenzyme plasminogen to active plasmin and plays a key role in cancer invasion and a variety of tissue remodelling processes such as wound healing, mammary gland involution and placental development. Elevated levels of uPA are associated with poor prognosis in many types of cancer. Applications: Suitable for use in ELISA, Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:50-1:100. Frozen sections & paraffin sections. Pretreatment with 0.05% Pronase E for 20 minutes. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.