U1000-18

Ubiquilin

Size

£863.00

SKU:: U1000-18
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein derived from an internal region of human Ubiquilin.
Clone:: 6A211
Format:: Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Extra Details:: Ubiquilin is a recently discovered protein that is involved in early onset Alzheimer’s disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the Ubiquilin protein contains ubiquitin-like domains, Ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimer’s and Parkinson’s diseases. Applications: Suitable for use in Immunoprecipitation, ELISA and Western Blot. Other applications have not been tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.