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U1000-17-ML490

Ubiquilin (MaxLight 490)

Size

£1,068.00

SKU:
U1000-17-ML490
Purity:
Purified by Protein A affinity chromatography
Storage Conditions:
4°C Do Not Freeze
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Recombinant protein corresponding to the C-terminal region of the human ubiquilin protein
Clone:
3B8A10
Format:
Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™490.
Extra Details:
MaxLight™ 490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Ubiquilin is a recently discovered protein that is involved in early onset Alzheimer’s disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the ubiquilin protein contains ubiquitin-like domains, ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimer’s and Parkinson’s diseases. Applications: Suitable for use in FLISA and Western Blot. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Shipping Conditions:
Blue Ice