U1000-17-BIOTIN
Ubiquilin (Biotin)
Size
£1,068.00
- SKU:
- U1000-17-BIOTIN
- Purity:
- Purified by Protein A affinity chromatography
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to the C-terminal region of the human ubiquilin protein
- Clone:
- 3B8A10
- Format:
- Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Biotin.
- Extra Details:
- Ubiquilin is a recently discovered protein that is involved in early onset Alzheimer’s disease. Ubiquilin binds to and promotes aggregation of presenilin proteins. Although the ubiquilin protein contains ubiquitin-like domains, ubiquilin appears to increase presenilin synthesis, rather than affect presenilin turnover. Ubiquilin is found in neuropathological lesions that are characteristic of Alzheimer’s and Parkinson’s diseases. Applications: Suitable for use in ELISA and Western Blot. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
- Shipping Conditions:
- Blue Ice