U0884-01

UK-1 (Antibiotic)

Size

£464.00

SKU:: U0884-01
Molecular Weight:: 386.4
Purity:: ~95% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 151271-53-3
Format:: Supplied as a white to pale pink solid.
Extra Details:: Antibiotic UK-1 is an unusual bis-benzoxazole metabolite isolated from a species of Streptomyces. It exhibits good antitumor activity but is devoid of antimicrobial activity. Antibiotic UK-1 acts as a magnesium ion-dependent DNA binding agent and inhibitor of human topoisomerase II. Source: Antibiotic UK-1 from Streptomyces Molecular Weight: ~386.4 Solubility: Soluble in DMSO. Limited solubility in water, methanol and ethanol. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.